C19H16N2O5
352.3 g/mol
원료의약품경고
Roxadustat
CAS808118-40-3
용도 분류
원료의약품
화합물 분류
아미드
주요 용도
의약 원료
Roxadustat is a compound that inhibits hypoxia-inducible factor prolyl hydroxylase, an enzyme involved in cellular oxygen sensing. It is an N-acylglycine derivative and is used as an active pharmaceutical ingredient in pharmaceutical manufacturing.
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitorEC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor
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CAS 808118-40-3
관련 화합물
유사구조 유사유사도 0.84
Roxadustat Impurity 2
CAS1421312-36-8
Roxadustat impurity for reference standard
참고동일 카테고리
Oxybutynin N-oxide
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active metabolite of oxybutynin
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anthelmintic drug impurity
참고동일 카테고리
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active pharmaceutical ingredient raw material
참고동일 카테고리
Boronophenylalanine B-10
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active pharmaceutical ingredient
참고same scaffold
4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid
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Pharmaceutical intermediate
참고same scaffold
Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
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pharmaceutical intermediate
참고same scaffold
4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid ethyl ester
CAS1809286-36-9
n.a
안전 참조
경고
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
식별자
IUPAC 이름
2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
InChIKey
YOZBGTLTNGAVFU-UHFFFAOYSA-N
SMILES
CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3
동의어 목록 (22)
- 8HO
- EX-A390
- Roxadustat (JAN/USAN/INN)
- ASP 1517
- Evrenzo
- Evrenzo (TN)
- FG 4592
- FG-4592,ASP1517
- Roxadustat
- Roxadustat (FG-4592)
- Roxadustat (Standard)
- roxadustatum