홈/화합물/원료의약품/N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide

C₂₉H₂₉N₉O₂

535.6 g/mol

원료의약품위험

N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide

CAS2728667-27-2EC884-819-6

용도 분류

원료의약품

화합물 분류

헤테로사이클

주요 용도

의약 원료

Zongertinib is a pharmaceutical raw material that functions as a selective, irreversible inhibitor of the HER2 tyrosine kinase. It covalently binds to the HER2 receptor, including exon 20 insertions, while sparing wild-type EGFR to reduce associated toxicities.

API for HER2-targeted kinase inhibitor formulationsCompound for manufacturing non-small cell lung cancer therapeutics

콘텐츠 범위: 이 페이지의 정보는 화학물질 식별 및 산업 공급·연구개발·제조 맥락을 대상으로 합니다. 치료 효능 주장, 의료 조언 또는 의약품 사용 지침에 해당하지 않습니다.

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CAS 2728667-27-2

안전 참조

건강 유해

환경 유해

위험

H360May damage fertility or the unborn child

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

식별자

IUPAC 이름

N-[1-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]pyrimido[5,4-d]pyrimidin-6-yl]piperidin-4-yl]prop-2-enamide

InChIKey

YSGNGFPNTLERCR-UHFFFAOYSA-N

SMILES

CC1=C(C=CC(=C1)NC2=NC=NC3=CN=C(N=C32)N4CCC(CC4)NC(=O)C=C)OC5=CC6=C(C=C5)N(C=N6)C

동의어 목록 (11)

Zongertinib (JAN/USAN/INN)
BI 1810631
Hernexeos (TN)
Zongertinib
Zongertinib (BI 1810631)
example I-01

N-(1-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl)acrylamide

관련 화합물

안전 참조