홈/화합물/의약 중간체/N2'-Deacetyl-N2'-[4-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]dithio]-4-methyl-1-oxopentyl]maytansine

C₄₆H₆₃ClN₄O₁₄S₂

995.6 g/mol

의약 중간체

N2'-Deacetyl-N2'-[4-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]dithio]-4-methyl-1-oxopentyl]maytansine

CAS1626359-62-3

용도 분류

의약 중간체

화합물 분류

기타

주요 용도

의약 중간체

This compound is a complex, ring-containing molecule with multiple amide and ether groups, used as a linker payload in antibody-drug conjugates for research and manufacturing applications.

antibody-drug conjugate linker payload

콘텐츠 범위: 이 페이지의 정보는 화학물질 식별 및 산업 공급·연구개발·제조 맥락을 대상으로 합니다. 치료 효능 주장, 의료 조언 또는 의약품 사용 지침에 해당하지 않습니다.

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CAS 1626359-62-3

관련 화합물

강한 관련구조 유사유사도 0.85

4-[[5-[[(2S)-1-[[(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-2-methyl-5-oxopentan-2-yl]disulfanyl]-1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxobutane-2-sulfonic acid

CAS1626359-59-8

antibody-drug conjugate linker payload

유사구조 유사유사도 0.74

(2,5-dioxopyrrolidin-1-yl) 4-[[3-[5-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-2-methyl-5-oxopentan-2-yl]sulfanyl-2,5-dioxopyrrolidin-1-yl]methyl]cyclohexane-1-carboxylate

CAS1228105-52-9

n.a

용도 관련동일 용도

Mal-(CH2)5-Val-Cit-PAB-Eribulin

CAS2130869-21-3

antibody-drug conjugate linker payload

용도 관련동일 용도

Py-MAA-Val-Cit-PAB-MMAE

CAS2247398-68-9

antibody-drug conjugate linker payload

용도 관련동일 용도

MC-GGFG-Exatecan

CAS1600418-29-8

antibody-drug conjugate linker payload

참고동일 카테고리

Tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

CAS1628047-84-6

pharmaceutical intermediate

참고동일 카테고리

1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

CAS1628047-87-9

pharmaceutical intermediate

참고동일 카테고리

Tert-Butyl 3-hydrazinylpiperidine-1-carboxylate dihydrochloride

CAS1628179-35-0

pharmaceutical intermediate for drug synthesis

식별자

IUPAC 이름

(2,5-dioxopyrrolidin-1-yl) 4-[[5-[[(2S)-1-[[(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-2-methyl-5-oxopentan-2-yl]disulfanyl]butanoate

InChIKey

LAVNQRWLLQGEIB-CUSRITNRSA-N

SMILES

C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON5C(=O)CCC5=O)C)\C)OC)(NC(=O)O2)O

동의어 목록 (3)

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