Abemaciclib mesylate is a salt form of abemaciclib, an orally available cyclin-dependent kinase (CDK) inhibitor that targets CDK4 and CDK6, with potential antineoplastic activity. It inhibits retinoblastoma protein phosphorylation, thereby arresting the cell cycle in the G1 phase and suppressing cancer cell growth.
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CAS 1231930-82-7
Abemaciclib
cell cycle inhibitor
Ganirelix
gonadotropin-releasing hormone antagonist
Clofarabine
antineoplastic antimetabolite nucleoside metabolic inhibitor
25-Hydroxycholecalciferol, 5-trans-
active pharmaceutical ingredient
Azane;N-[1-[4-[4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-phenoxyphenyl]ethyl]acetamide;formic acid;methane;pentadecahydrate;dihydrochloride
active pharmaceutical ingredient
N-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid
NCJPFQPEVDHJAZ-UHFFFAOYSA-N
CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O