C23H20F3N5O2S2
519.6 g/mol
원료의약품경고
Dabrafenib
CAS1195765-45-7EC689-166-9
용도 분류
원료의약품
화합물 분류
헤테로사이클
주요 용도
의약 원료
Dabrafenib is a pharmaceutical compound that inhibits the B-Raf enzyme, which is involved in cell growth regulation. It is used in the manufacturing of medications targeting cancers associated with a mutated BRAF gene.
active pharmaceutical ingredient for cancer researchlaboratory reagent for B-Raf inhibition studies
콘텐츠 범위: 이 페이지의 정보는 화학물질 식별 및 산업 공급·연구개발·제조 맥락을 대상으로 합니다. 치료 효능 주장, 의료 조언 또는 의약품 사용 지침에 해당하지 않습니다.
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CAS 1195765-45-7
관련 화합물
강한 관련동일 모체 구조
Dabrafenib mesylate
CAS1195768-06-9
active pharmaceutical ingredient
유사구조 유사유사도 0.81
N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide
CAS1195768-23-0
research compound
참고동일 카테고리
(-)-Verbenone
CAS1196-01-6
pharmaceutical reference standard
참고동일 카테고리
4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrochloride
CAS1196074-08-4
active pharmaceutical ingredient
참고동일 카테고리
Olprinone hydrochloride
CAS119615-63-3
cardiotonic active pharmaceutical ingredient
참고동일 카테고리
2-[2-[1-(4-chloro-2,3,5,6-tetradeuteriobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid
CAS1196151-16-2
deuterated pharmaceutical reference standard
안전 참조
경고
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects
식별자
IUPAC 이름
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
InChIKey
BFSMGDJOXZAERB-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F
동의어 목록 (22)
- P06
- Dabrafenib (USAN)
- 1195765-45-7 (free base)
- BRAF Inhibitor GSK2118436
- DABRAFENIB, KB-57246
- Dabrafenib
- Dabrafenib (Free Base)
- Dabrafenib (GSK2118436)
- Dabrafenib (Standard)
- GSK 2118436A
- Tafinlar
- dabrafenibum