C12H20N4O6S
348.38 g/mol
원료의약품경고
Relebactam
CAS1174018-99-5
용도 분류
원료의약품
화합물 분류
헤테로사이클
주요 용도
의약 원료
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, structurally similar to avibactam, and serves as an active pharmaceutical ingredient used in combination with imipenem and cilastatin. It features a piperidine ring that imparts a positive charge, reducing bacterial export, and was approved by the FDA in 2019 as part of the Recarbrio® combination product for treating complicated urinary tract infections, pyelonephritis, and complicated intra-abdominal infections in adults.
active pharmaceutical ingredient in beta-lactamase inhibitor combinationscomponent of combination therapy with imipenem and cilastatin
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CAS 1174018-99-5
관련 화합물
강한 관련동일 모체 구조
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beta-lactamase inhibitor
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참고same scaffold
1,1-Dimethylethyl 4-[[[(1R,2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl]amino]-1-piperidinecarboxylate
CAS1174020-64-4
research compound
안전 참조
경고
H373May cause damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
식별자
IUPAC 이름
[(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
InChIKey
SMOBCLHAZXOKDQ-ZJUUUORDSA-N
SMILES
C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)NC3CCNCC3
동의어 목록 (19)
- (-)-relebactam monohydrate
- MK-7655 MONOHYDRATE
- MK-7655A COMPONENT RELEBACTAM
- Relebactam
- Relebactam (Standard)
- Relebactam anhydrous
- US8487073, 1A
- relebactamum