VC-PAB-MMAE is a pharmaceutical intermediate used in the manufacturing of antibody-drug conjugates. It is a complex, highly functionalized compound with multiple amide bonds and stereocenters, reflecting its role as a building block for targeted therapeutics.
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CAS 644981-35-1
[4-[[(2S)-2-[[(2S)-2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate
Antibody-drug conjugate payload
Acetylene-linker-Val-Cit-PABC-MMAE
antibody-drug conjugate linker payload
SuO-Glu-Val-Cit-PAB-MMAE
抗体-薬物複合体リンカーペイロード
SC-VC-PAB-MMAE
antibody-drug conjugate research compound
Conjugated form of mc-vc-PAB-MMAE
antibody-drug conjugate intermediate
4-Bromo-2,3-difluorobenzaldehyde
医薬中間体
イソバニリン酸
医薬中間体
3-Phenylpropanoyl chloride
医薬中間体
[4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate
WZEAGSMYTVSXQA-XZZQEHRXSA-N
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